Cryo-electron microscopy (Cryo-EM) and drug design
Our research program is focused on exploring frontiers in structural biology and drug design using cryo electron microscopy (cryo-EM), with the central goal of accelerating the development of effective therapeutic agents. The program is guided by two overarching themes:
A highly focused team effort to use high-resolution cryo-EM imaging of native protein complexes to design effective therapeutic agents targeting key drivers of diseases such as cancer and brain disorders.
An interdisciplinary approach towards developing next generation technologies in cryo-EM and related methods using automated workflows coupled with advanced image processing and machine learning.