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Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes

Wohlbold TJ, Podolsky KA, Chromikova V, Kirkpatrick E, Falconieri V, Meade P, Amanat F, Tan J, tenOever BR, Tan GS, Subramaniam S, Palese P, Krammer F. Nature Microbiology 2: 1415-24 (2017)

Building bridges between cellular and molecular structural biology

Building bridges between cellular and molecular structural biology

Patwardhan A, Brandt R, Butcher SJ, Collinson L, Gault D, Grünewald K, Hecksel C, Huiskonen JT, Iudin A, Jones ML, Korir PK, Koster AJ, Lagerstedt I, Lawson CL, Mastronarde D, McCormick M, Parkinson H, Rosenthal PB, Saalfeld S, Saibil HR, Sarntivijai S, Solanes Valero I, Subramaniam S, Swedlow JR, Tudose I, Winn M, Kleywegt GJ. […]

Cryo-EM: beyond the microscope

Cryo-EM: beyond the microscope

Earl LA, Falconieri V, Milne JLS, Subramaniam S. Current Opinion in Structural Biology 46: 71-78 (2017)

Power Grid Protection of the Muscle Mitochondrial Reticulum

Power Grid Protection of the Muscle Mitochondrial Reticulum

Glancy B, Hartnell LM, Combs CA, Fenmou A, Sun J, Murphy E, Subramaniam S, Balaban RS. Cell Reports 19: 487-96 (2017)

Structural basis of kainate subtype glutamate receptor desensitization

Structural basis of kainate subtype glutamate receptor desensitization

Meyerson JR, Chittori S, Merk A, Rao P, Han TH, Serpe M, Mayer ML, Subramaniam S. Nature 537: 567-71 (2016)

Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase

Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase

Puppala AK, French RL, Matthies D, Baxa U, Subramaniam S, Simonović M. Scientific Reports 6: 32563 (2016)

Resolution advances in cryo-EM enable application to drug discovery

Resolution advances in cryo-EM enable application to drug discovery

Subramaniam S, Earl LA, Falconieri V, Milne JLS, Egelman EH. Current Opinion in Structural Biology 41: 194-202 (2016)

Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry

Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry

Tran EE, Nelson EA, Bonagiri P, Simmons JA, Shoemaker CJ, Schmaljohn CS, Kobinger GP, Zeitlin L, Subramaniam S, White JM. Journal of Virology 90: 7618-27 (2016)

Cryo-EM of viruses and vaccine design

Cryo-EM of viruses and vaccine design

Earl LA, Subramaniam S. Proceedings of the National Academy of Sciences USA 113: 8903-05 (2016)

The democratization of cryo-EM

The democratization of cryo-EM

Stuart DI, Subramaniam S, Abrescia NGA. Nature Methods 13: 607-08 (2016)

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Program in Cryo-EM Guided Drug Design
Faculty of Medicine
Djavad Mowafaghian Centre for Brain Health
Room 3404 – 2215 Wesbrook Mall
Vancouver, BC Canada V6T 1Z3
Tel 604 822 8073
Website electron.med.ubc.ca
Email cryoem.lab@ubc.ca
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