Combatting COVID-19: UBC’s contributions to overcoming the pandemic

The University of British Columbia Magazine | March 13, 2023

A research team, led by Professor Sriram Subramaniam in the UBC Department of Biochemistry and Molecular Biology, made several significant breakthroughs by using massive microscopes — up to 13 feet tall. Using cryo-electron microscopy, the team captured images of the COVID-19 spike protein at near-atomic resolution to assess the binding of different antibody treatments to the virus. By September 2020, the researchers determined that antibody-based drug Ab8 prevented and neutralized the virus.