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Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9

Zhu X, Clarke R, Puppala AK, Chittori S, Merk A, Merrill BJ, Simonovic M, Subramaniam S.

Nature Structural & Molecular Biology 26: 679-85 (2019)

Program in Cryo-EM Guided Drug Design
Faculty of Medicine
Djavad Mowafaghian Centre for Brain Health
Room 3404 – 2215 Wesbrook Mall
Vancouver, BC Canada V6T 1Z3
Tel 604 822 8073
Website electron.med.ubc.ca
Email cryoem.lab@ubc.ca
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