Microscope technique brings big resolution at low temperatures
Cryo-electron microscopy is a technique that can be used to determine the structures of biological molecules like proteins to high resolution. Recent changes in technology and computing over the past few years have suddenly made it possible to visualize proteins at near-atomic resolution, meaning that the positions of individual amino acids and even atoms can […]
Foundations of the Kinetochore
The eukaryotic genome is structurally coordinated by histones, small disc-like protein complexes that are each wrapped twice by the DNA double helix. In addition to helping pack the long strands of DNA, histones have a variety of functions that regulate the use of the genome to express proteins. These histone-DNA complexes are called nucleosomes. When […]